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Tocris Bioscience™ Bumetanide
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Catalog No. 310850
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Na+/2Cl-/K+ (NKCC) symporter inhibitor

Bumetanide is a loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide (Cat. No. 3109). Bumetanide improves electrophysiological, pathological and cognitive deficits in APOE4 knock-in mice. RNA sequencing of neurons derived from APOE4 induced pluripotent stem cell (iPSC) shows Bumetanide reverses Alzheimer's disease transcriptomic signatures.

Chemical Identifiers

CAS 28395-03-1
Molecular Formula C17H20N2O5S

Specifications

Quantity 50 mg
Formula Weight 364.42
Purity 98%
Molecular Weight (g/mol) 364.416
Chemical Name or Material Bumetanide

Safety and Handling

Recommended Storage Store at Room Temperature
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