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Bumetanide, Tocris Bioscience™

Catalog Number 310850
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Quantity:
50 mg
This item is not returnable. View return policy
28395-03-1
C17H20N2O5S
364.416
MAEIEVLCKWDQJH-UHFFFAOYSA-N
bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
2471
CHEBI:3213
3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2
This item is not returnable. View return policy
28395-03-1
C17H20N2O5S
364.416
MAEIEVLCKWDQJH-UHFFFAOYSA-N
bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
2471
CHEBI:3213
3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Na+/2Cl-/K+ (NKCC) symporter inhibitor

Bumetanide is a loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide (Cat. No. 3109). Bumetanide improves electrophysiological, pathological and cognitive deficits in APOE4 knock-in mice. RNA sequencing of neurons derived from APOE4 induced pluripotent stem cell (iPSC) shows Bumetanide reverses Alzheimer's disease transcriptomic signatures.
Quantity 50 mg
Formula Weight 364.42
Percent Purity 98%
Chemical Name or Material Bumetanide
Recommended Storage Store at Room Temperature
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