Bupivacaine hydrochloride monohydrate, 98+%

Catalog No.	Quantity
AAJ6283503	1 g
AAJ6283506	5 g
AAJ6283514	25 g

Catalog No. AAJ6283503 Supplier Thermo Scientific Chemicals Supplier No. J6283503

Description

Inhibits TREK-1 channels and depolarizes the cell membrane | CAS: 73360-54-0 | C18H31ClN2O2 | 342.908 g/mol

It is employed as Na+ channel blocker, local anesthetic and cAMP production inhibitor. It acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist, EC 3.1.1.8 (cholinesterase) inhibitor and EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is employed as Na+ channel blocker, local anesthetic and cAMP production inhibitor. It acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist, EC 3.1.1.8 (cholinesterase) inhibitor and EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor.

Solubility
Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Specifications

Chemical Identifiers

• CAS: 73360-54-0
• Molecular Formula: C18H31ClN2O2
• Molecular Weight (g/mol): 342.908
• MDL Number: MFCD00078956
• InChI Key: HUCIWBPMHXGLFM-UHFFFAOYSA-N
• Synonym: bupivacaine hydrochloride monohydrate, lac-43, marcaine tn, +/--1-butyl-2',6'-pipecoloxylidide monohydrochloride, monohydrate, 1-butyl-n-2,6-dimethylphenyl piperidine-2-carboxamide hydrate hydrochloride, bupivacaine hydrate hydrochloride, bupivacaine hcl h2-o, 2-piperidinecarboxamide, 1-butyl-n-2,6-dimethylphenyl-, monohydrochloride, monohydrate, bupivacaine hydrochloride ep, 1-butyl-n-2,6-dimethylphenyl piperidine-2-carboxamide hydrochloride hydrate
• PubChem CID: 5282419
• IUPAC Name: 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide;hydrate;hydrochloride
• SMILES: CCCCN1CCCCC1C(=O)NC2=C(C=CC=C2C)C.O.Cl

• Melting Point: 255°C to 259°C
• Color: White
• Quantity: 1 g
• UN Number: UN2811
• Merck Index: 14,1495
• Solubility Information: Soluble in water to 50 mM,in DMSO to 100 mM and in ethanol to 100 mM.
• Formula Weight: 342.9
• Percent Purity: ≥98%
• Physical Form: Powder
• Chemical Name or Material: Bupivacaine hydrochloride monohydrate

Safety and Handling

Hazard Category	H300+H310+H330
Hazard Statement	GHS H Statement H300-H310-H330 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Precautionary Statement	P260-P262-P264b-P270-P271-P280-P284-P301+P310-P302+P350-P304+P340-P310-P330-P361-P363-P501c
DOTInformation	Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber	241-917-8
RTECSNumber	TK6125000
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only