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Bupivacaine

Catalog No. AAJ6274203
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Catalog No. AAJ6274203 Supplier Thermo Scientific Chemicals Supplier No. J6274203
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Description

Bupivacaine, CAS # 38396-39-3, is a potent and long-acting in vivo local anesthetic agent. | CAS: 38396-39-3 | C18H28N2O | 288.44 g/mol

Bupivacaine acts as a potent and long-acting local anesthetic agent in vivo. At 100 μM, it has been reported to inhibit the uptake of dopamine in striatal synaptosomes by 47%.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Application

  • Bupivacaine has been shown to activate the AMPKα/BDNF signaling pathway in spinal astrocytes
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 38396-39-3
Molecular Formula C18H28N2O
Molecular Weight (g/mol) 288.44
MDL Number MFCD00243007,MFCD00941462
InChI Key LEBVLXFERQHONN-UHFFFAOYNA-N
Synonym bupivacaine, 1-butyl-n-2,6-dimethylphenyl piperidine-2-carboxamide, dl-bupivacaine, marcaine, bupivacaina, carbostesin, bupivacainum, sensorcaine, anekain, +--bupivacaine
PubChem CID 2474
ChEBI CHEBI:77431
IUPAC Name 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
SMILES CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C

Specifications

Melting Point 106°C to 110°C
Color White
Quantity 1 g
UN Number UN2811
Solubility Information Soluble in water,ethanol,chloroform (slightly ),and acetone (slightly ).
Formula Weight 288.43
Physical Form Crystalline Powder
Chemical Name or Material Bupivacaine

Safety and Handling

Hazard Category H300+H310+H330
Hazard Statement GHS H Statement
H300-H310-H330
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
Precautionary Statement P260-P262-P264b-P270-P271-P280-P284-P301+P310-P302+P350-P304+P340-P310-P330-P361-P363-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: II; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 253-911-2
TSCA Yes
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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