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Invitrogen™ Butyrylcholinesterase Monoclonal Antibody (3E8)
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Catalog No. HAH0020102
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200 μg
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HAH0020102 200 μg
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Catalog No. HAH0020102 Supplier Invitrogen™ Supplier No. HAH0020102
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Mouse Monoclonal Antibody

HAH 002-01-02 has specificity for butyrylcholinesterase from human serum or plasma. Crossreactivity to BtChE from other species has not been tested. HAH 002-01-02 has been successfully used in ELISA techniques. HAH 002-01-02 reacts with BtChE from normal serum when tested in sandwich ELISA. This antibody can be used as both the capture and detection antibody or an alternative antibody against BtChE can be used as capture antibody. In addition, it can be used in crossed immunoelectrophoresis followed by incubation of the gel with HAH 002-01-02. In immunoblotting after SDS-PAGE no reaction is seen with either the reduced or with the non-reduced form of BtChE. No reaction is seen with acetylcholinesterase from human nervous tissue and erythrocytes. The HAH 002-01-02 immunogen is Butyrylcholinesterase found in human plasma cells.

Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Butyrylcholinesterase
Applications ELISA
Classification Monoclonal
Clone 3E8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.4
Gene BCHE
Gene Accession No. P06276
Gene Alias acylcholine acylhydrolase; BCHE; BtChE; butylcholinesterase; butyrylcholine esterase; butyrylcholinesterase; C730038G20Rik; CHE1; CHE2; Choline esterase II; cholinesterase; cholinesterase (serum) 2; cholinesterase 1; E1; EC 3.1.1.8; pseudocholinesterase
Gene Symbols BCHE
Host Species Mouse
Immunogen Butyrylcholinesterase isolated from human plasma.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 590
Target Species Human
Content And Storage -20°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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