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BUV496 Mouse Anti-Human CD3, BD Horizon™

Catalog No. BDB569786 Shop All BD Biosciences Products
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BDB569786 50 μg
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Description

Mouse Monoclonal Antibody

CD3 Monoclonal Antibody Specifically detects CD3 in Human Samples. It is validated for Flow Cytometry.

The SK7 (Leu-4) monoclonal antibody specifically binds to the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex consists of at least six proteins ranging from 20 to 30 kDa. The CD3 antigen is noncovalently associated with either α/β or γ/δ TCR (70 to 90 kDa). It is found on 61% to 85% of normal peripheral blood lymphocytes, 60% to 85% of thymocytes, and on Purkinje cells in the cerebellum. The soluble form of this antibody has a mitogenic effect on most peripheral blood T lymphocytes when appropriate functional monocytes are present.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3
Applications Flow Cytometry
Classification Monoclonal
Clone SK7 (also known as Leu-4)
Concentration 0.2 mg/mL
Conjugate Brilliant Ultraviolet 496
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias CD3-epsilon; CD3E; Leu4; T-cell surface antigen T3/Leu-4 epsilon chain; T3E
Host Species Mouse
Immunogen Human Thymocytes
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 916
Target Species Human
Content And Storage The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions and unconjugated antibody and free dye were removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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