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Invitrogen™ c-Fos Monoclonal Antibody (T.142.5)
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Catalog No. PIMA515055
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100 μL
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PIMA515055 100 μL
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Catalog No. PIMA515055 Supplier Invitrogen™ Supplier No. MA515055
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other Fos proteins, including FosB, FRA1 and FRA2.

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen c-Fos
Applications ChIP Assay, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone T.142.5
Concentration 108 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 50% glycerol, 100μg/mL BSA, 0.15M NaCl and <0.02% sodium azide; pH 7.5
Gene FOS
Gene Accession No. P01100, P01101, P12841
Gene Alias activator protein 1; AP-1; cellular oncogene c-fos; cellular oncogene fos; cFos; C-FOS; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ murine osteosarcoma viral oncogene homolog B; FBJ osteosarcoma oncogene; FBJ osteosarcoma oncogene B; FBJ osteosarcoma viral oncogene isoform deltaFosb-2; FOS; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; Fosb; FosB proto-oncogene, AP-1 transcription factor subunit; fra-2; G0/G1 switch regulatory protein 7; G0S7; I79_009428; p55; protein fosB; proto-oncogene cFOS; proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Symbols FOS
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the sequence of human c-Fos.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14281, 2353, 314322
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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