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c-Fos Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993387
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50-199-3387 10 μL
50-199-3386 100 μL
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Catalog No. 50-199-3387 Supplier Active Motif Supplier No. 61422
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Description

Rabbit Polyclonal Antibody

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.

Specifications

Antigen c-Fos
Applications Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene FOS
Gene Accession No. P01100
Gene Alias activator protein 1; AP-1; BOS_11003; cellular oncogene c-fos; Cellular oncogene fos; cFos; c-fos; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ osteosarcoma oncogene; Fos; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 7; G0S7; I79_009428; LOC100338345; murine FBJ osteosarcoma viral (v-fos) oncogene homolog; p55; proto-oncogene cFOS; Proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Symbols FOS
Host Species Rabbit
Immunogen This antibody was raised against a peptide within human c-Fos.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2353
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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