Invitrogen™ C-Peptide Monoclonal Antibody (C-PEP-01)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA119159

Catalog No. 01-675-929

Description

This antibody reacts specifically with C-peptide, a part of the proinsulin molecule. Proinsulin consists of three parts: C-peptide and two long strands of amino acids (alpha and beta chains; later become linked together to form the insulin molecule). No cross-reactivity with insulin or other peptide hormones or proteins was observed.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified.

Specifications

• Antigen: C-Peptide
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P01308
• Gene Symbols: INS
• Immunogen: Human C-peptide conjugated to BSA.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Immunocytochemistry
• Clone: C-PEP-01
• Conjugate: Unconjugated
• Gene: INS
• Gene Alias: Cpeptide; IDDM; IDDM1; IDDM2; ILPR; INS; Ins1; Ins-1; Ins2-rs1; insulin; insulin 1; Insulin A chain; Insulin B chain; insulin I; insulin-1; Insulin-1 A chain; Insulin-1 B chain; IRDN; MODY10; preproinsulin; proinsulin
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3630
• Content And Storage: 4°C, do not freeze
• Form: Liquid

Safety and Handling

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