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c-Rel Monoclonal Antibody (1RELAH5), eBioscience™, Invitrogen™

Rat Monoclonal Antibody

$462.00

Specifications

Antigen c-Rel
Clone 1RELAH5
Concentration 0.5 mg/mL
Applications Western Blot
Classification Monoclonal
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-245-577
Encompass_Preferred
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Invitrogen™
14611182
100 μg
Each of 1 for $462.00
Only null left
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Description

Description

Description: The 1RELAH5 monoclonal antibody reacts with mouse c-Rel. c-Rel is a 65 kDa hematopoietic lineage-restricted member of the NF-kB family of transcription factors. In the thymus, c-Rel is upregulated in regulatory T cells (Treg) when compared to other CD4+ thymocytes. c-Rel is believed to play a critical role in thymic Treg (nTreg) development, but is not necessary for TGF beta-mediated T reg (iTreg) differentiation. C-Rel is also involved in proliferation and survival in mature T cells. Applications Reported: This 1RELAH5 antibody has been reported for use in western blotting. Applications Tested: This 1RELAH5 antibody has been tested by western blot analysis of mouse splenocytes. This can be used at 1-5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA., RELB (604758), NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the 'Rel domain, ' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007).
Specifications

Specifications

c-Rel
0.5 mg/mL
Monoclonal
Liquid
RUO
P15307
IgG2a κ
Affinity chromatography
Antibody
1RELAH5
Western Blot
Unconjugated
Rat
Mouse
19696
Primary
4°C
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SDS
Documents

Documents

Product Certifications

For Research Use Only.

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