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c-Rel Rat anti-Mouse, Clone: 1RELAH5, eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$119.00 - $304.00

Specifications

Antigen c-Rel
Clone 1RELAH5
Target Species Mouse
Conjugate Unconjugated
Isotype IgG2a, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-245-576 Non-distribution product as customer accommodation.
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Invitrogen
14611180
25 μg Each for $119.00
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50-245-577 Non-distribution product as customer accommodation.
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Invitrogen
14611182
100 μg Each for $304.00
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Description

Description

Description: The 1RELAH5 monoclonal antibody reacts with mouse c-Rel. c-Rel is a 65 kDa hematopoietic lineage-restricted member of the NF-kB family of transcription factors. In the thymus, c-Rel is upregulated in regulatory T cells (Treg) when compared to other CD4+ thymocytes. c-Rel is believed to play a critical role in thymic Treg (nTreg) development, but is not necessary for TGF beta-mediated T reg (iTreg) differentiation. C-Rel is also involved in proliferation and survival in mature T cells. Applications Reported: This 1RELAH5 antibody has been reported for use in western blotting. Applications Tested: This 1RELAH5 antibody has been tested by western blot analysis of mouse splenocytes. This can be used at 1-5 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA, RELB (604758), NFKB1, and NFKB2. These proteins are related through a highly conserved N-terminal region termed the  ft.Rel domain, ft. which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (Belguise and Sonenshein, 2007).
Specifications

Specifications

c-Rel
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C
1RELAH5
Unconjugated
Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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