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C11orf30 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735260 Shop All Proteintech Group Inc Products
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50-173-5260 150 μL
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Catalog No. 50-173-5260 Supplier Proteintech Group Inc Supplier No. 262121AP150UL
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Description

Rabbit Polyclonal Antibody

MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme.The protein encoded by this gene is one of the highly conserved mini-chromosome maintece proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Specifications

Antigen C11orf30
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.46 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene EMSY
Gene Accession No. Q7Z589
Gene Alias C11orf30, EMSY, GL002, Protein EMSY
Gene Symbols EMSY
Host Species Rabbit
Immunogen C11orf30 Fusion Protein Ag23974
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56946
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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