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Invitrogen™ C19orf10 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 500P259BT50UG

Encompass_Preferred

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Catalog No. 500P259BT50


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Description

Description

AA Sequence of recombinant protein: MVSEPTTVPF DVRPGGVVHS FSQDVGPGNK FTCTFTYASQ GGTNEQWQMS LGTSEDSQHF TCTIWRPQGK SYLYFTQFKA ELRGAEIEYA MAYSKAAFER ESDVPLKSEE FEVTKTAVSH RPGAFKAELS KLVIVAKAAR SEL. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Murine SF-20. Anti-Murine SF-20-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect mSF-20 by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Murine SF-20 (500-P259) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant mSF-20. Western Blot: To detect mSF-20 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant mSF-20 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P259BT-1MG will be provided as 2 x 500 μg

The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells. IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types. IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation. Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression. IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity, suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

C19orf10
Polyclonal
Biotin
MYDGF
C19orf10; CS010; D17Wsu104e; EUROIMAGE1875335; IL 25; IL 27; Il25; IL27; IL27w; interleukin 25; interleukin 27 working designation; Interleukin25; interleukin-25; LOC501282; Ly6elg; Mydgf; myeloid derived growth factor; myeloid-derived growth factor; R33729 1; R33729_1; R337291; SF20; similar to lymphocyte antigen 6 complex, locus E ligand; stromal cell-derived growth factor SF20; UPF0556 protein C19orf10; UPF0556 protein C19orf10 homolog
Rabbit
Antigen Affinity Chromatography
RUO
28106
-20°C
Lyophilized
ELISA, Western Blot
0.1-1.0 mg/mL
PBS with no preservative
Q9CPT4
MYDGF
E.coli-derived, 15.8 kDa Recombinant Murine SF-20.
50 μg
Primary
Mouse
Antibody
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