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Invitrogen™ C1q Monoclonal Antibody (JL-1), Biotin
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Catalog No. MA140312
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MA140312 50 μg
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Catalog No. MA140312 Supplier Invitrogen™ Supplier No. MA140312
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Description

Mouse Monoclonal Antibody

MA1-40312 detects C1q from mouse samples. MA1-40312 has been successfully used in immunohistochemistry (frozen), ELISA, immunofluorescence, functional assays and Western blot applications. The MA1-40312 immunogen is purified mouse C1q. Positive control: Spleen and kidney tissue of wild-type mice ; Negative control: Spleen and kidney tissue of C1q -/- mice.

C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
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Specifications

Antigen C1q
Applications ELISA, Functional Assay, Immunohistochemistry (Frozen), Western Blot
Classification Monoclonal
Clone JL-1
Concentration 0.1 mg/mL
Conjugate Biotin
Formulation PBS with 0.1% BSA and 0.02% sodium azide
Gene C1QA
Gene Accession No. P02745, P02746, P02747, P14106, P31720, P31721, P31722, P98086, Q02105
Gene Alias AI255395; AI385742; C1q; C1qa; C1qb; C1qc; C1Q-C; C1QG; Ciqc; complement C1q A chain; complement C1q B chain; complement C1q C chain; complement C1q chain A; complement C1q chain B; complement C1q subcomponent subunit A; complement C1q subcomponent subunit A-like protein; Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit C; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component 1, q subcomponent, B chain; complement component 1, q subcomponent, beta polypeptide; complement component 1, q subcomponent, C chain; complement component 1, q subcomponent, c polypeptide; complement component 1, q subcomponent, gamma polypeptide; complement component C1q, A chain; complement component C1q, B chain; complement subcomponent C1q chain B
Gene Symbols C1QA, C1QB, C1qc
Host Species Mouse
Immunogen Purified mouse C1q.
Purification Method Protein G
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12259, 12260, 12262, 29687, 298566, 362634, 712, 713, 714
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2b
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