Invitrogen™ C1QA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529586

Catalog No. PIPA529586

Description

Recommended positive controls: human plasma, mouse spleen. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.

Specifications

• Antigen: C1QA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: C1qa
• Gene Alias: AI255395; C1q; C1QA; complement C1q A chain; complement C1q chain A; complement C1q subcomponent subunit A; complement component 1, q subcomponent, A chain; complement component 1, q subcomponent, alpha polypeptide; complement component C1q, A chain
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 712
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.18 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P02745
• Gene Symbols: C1qa
• Immunogen: Recombinant protein encompassing a sequence within the center region of human C1qA. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG