C2 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-5588	150 μL

Catalog No. 50-173-5588 Supplier Proteintech Group Inc Supplier No. 271751AP150UL

Description

Rabbit Polyclonal Antibody

Component C2 is a serum glycoprotein that functions aspart of the classical pathway of the complement system. ActivatedC1 cleaves C2 into C2a and C2b. The serine proteinase C2a thencombines with complement factor 4b to create the C3 or C5convertase. Deficiency of C2 has been reported to associated withcertain autoimmune diseases and SNPs in this gene have beenassociated with altered susceptibility to age-related maculardegeneration. This gene localizes within the class III region ofthe MHC on the short arm of chromosome 6. Alternative splicingresults in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publicationsbut their full-length sequence has not been determined.

Specifications

• Antigen: C2
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.23 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: C2
• Gene Accession No.: P06681
• Gene Alias: C2, C3/C5 convertase, CO2, Complement C2, complement component 2
• Gene Symbols: C2
• Host Species: Rabbit
• Immunogen: C2 Fusion Protein Ag25690
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 717
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG