Invitrogen™ CA19-9 Monoclonal Antibody (121SLE)

Catalog No.	Quantity
01-675-975	100 μg

Catalog No. 01-675-975 Supplier Invitrogen™ Supplier No. MA119211

Description

Mouse Monoclonal Antibody

This antibody recognizes Sialyl Lewis a-containing glycolipids (extracellular plasma membrane leaflet antigens). For IHC (P), heat mediated antigen retrieval in sodium citrate is recommended.

Mucin glycoprotein is a Sialyl Lewis A structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewis A and/or Lewis B blood group antigens. In normal tissues, sialyl Lewis A antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings.

Specifications

• Antigen: CA19-9
• Applications: ELISA, Immunohistochemistry (Paraffin)
• Classification: Monoclonal
• Clone: 121SLE
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 15mM sodium azide; pH 8
• Gene Alias: CA19 9; CA19.9; CA-19.9
• Host Species: Mouse
• Immunogen: Immunoprecipitate obtained after immunodiffusion of MAb 19-9 and mucins isolated from an ovarian cyst of a 0Le(a+b-) patient.
• Purification Method: sequential chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: 4°C, do not freeze
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM