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CACNB4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731781 Shop All Proteintech Group Inc Products
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50-173-1781 150 μL
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Catalog No. 50-173-1781 Supplier Proteintech Group Inc Supplier No. 177701AP150UL
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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen CACNB4
Applications Western Blot
Classification Polyclonal
Concentration 0.16 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CACNB4
Gene Accession No. D4A055, O00305, Q8R0S4
Gene Alias CAB4, CACNB4, CACNLB4, EA5, EJM
Gene Symbols Cacnb4
Host Species Rabbit
Immunogen CACNB4 Fusion Protein Ag12178
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12298, 58942, 785
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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