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Invitrogen™ CACNG3 Polyclonal Antibody
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Catalog No. PIPA5109290
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100 μL
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PIPA5109290 100 μL
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Catalog No. PIPA5109290 Supplier Invitrogen™ Supplier No. PA5109290
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Description

Rabbit Polyclonal Antibody

Positive Control: SH-SY-5Y, rat brain tissue.

Calcium Channel gamma-3 is a member of voltage dependent calcium channels (VDCCs) which allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal, and important in the genesis of synaptic transmission in discrete hippocampal fields. Calcium Channel gamma-3 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. Further, Calcium Channel gamma-3 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. Calcium Channel gamma-3 gene dysfunction is a susceptibility locus for childhood absence epilepsy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CACNG3
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4
Gene Cacng3
Gene Accession No. O60359, Q8VHX0
Gene Alias Cacng3; CACNLB3; calcium channel, voltage-dependent, gamma subunit 3; calcium voltage-gated channel auxiliary subunit gamma 3; CaVgamma3; neuronal voltage-gated calcium channel gamma-3 subunit; TARP gamma-3; transmembrane AMPAR regulatory protein gamma-3; Voltage-dependent calcium channel gamma-3 subunit; voltage-gated calcium channel gamma subunit
Gene Symbols Cacng3
Host Species Rabbit
Immunogen Synthetic peptide within rat CACNG3 aa 192-241.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10368, 140724
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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