Cadherin 13/CDH13/T-cadherin Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304967AT

Catalog No. 50-156-9152

Description

The recommended shelf life for this product is 1 year from date of receipt.

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintece of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that.

Specifications

• Antigen: Cadherin 13/CDH13/T-cadherin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH13
• Gene Alias: Cadherin-13; Truncated cadherin; T-cadherin; T-cad; Heart cadherin; H-cadherin; P105; CDH13; CDHH
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1012
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: P55290
• Gene Symbols: CDH13
• Immunogen: Between 475 and 525
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG