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Epredia™ Lab Vision™ Cadherin-P Ab-1, Mouse Monoclonal Antibody
Obtain accurate, reproducible results in immunohistochemistry experiments with Epredia™ Cadherin-P Ab-1, Mouse Monoclonal Antibody.
Specifications
| Antigen | Cadherin-P/P-cadherin Ab-1 |
|---|---|
| Clone | 56C1 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Form | Quantity | Price | Quantity & Availability | ||||
|
MS1741R7
|
Epredia™
MS1741R7 |
Prediluted | 7 mL | N/A | N/A | N/A | |||
|
MS1741S0
|
Epredia™
MS1741S0 |
Supernatant | 100 μL | N/A | N/A | N/A | |||
|
MS1741S1
|
Epredia™
MS1741S1 |
Supernatant | 500 μL | N/A | N/A | N/A | |||
|
MS1741S
|
Epredia™
MS1741S |
Supernatant | 1 mL | N/A | N/A | N/A | |||
Description
Cadherins are calcium dependent cell adhesion molecules, which play important roles in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. They are expressed in a tissue specific manner and are required for assembly of cells into solid tissue. Individual cadherin molecules are known to cooperate with each other to form a linear cell adhesion zipper. In adhesion junctions cadherins are bound to Beta and gamma catenins which in turn bind to alpha catenin, an actin binding protein. Cadherins play important part in tumor invasion and metastasis. P-cadherin is selectively expressed in basal and parabasal layers of stratified epithelia. It may be involved in the final stages of tumor progression in epidermal carcinoma. Changes in P-cadherin expression have been implicated in breast and melanocytic tumors.Host Species: Mouse
Clone: 56C1
Isotype: IgG1
Species Reactivity: Human. Others not known.
Epitope: External domain
Immunogen: Recombinant protein corresponding to extracellular domain of human cadherin-P
Molecular Weight: 120kDa
Positive Control: Skin
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Note:
USA: IVD; Int'l: IVD
Specifications
| Cadherin-P/P-cadherin Ab-1 | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| RUO | |
| Recombinant protein corresponding to extracellular domain of human P-cadherin |
| 56C1 | |
| Monoclonal | |
| Mouse | |
| Junction Protein | |
| Primary |
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