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Invitrogen™ Caffeine Monoclonal Antibody (F1-P2B1G1)
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Catalog No. PIMA514725
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100 μg
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PIMA514725 100 μg
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Catalog No. PIMA514725 Supplier Invitrogen™ Supplier No. MA514725
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Description

Mouse Monoclonal Antibody

MA5-14725 targets Caffeine in ELISA, IP, and RIA applications and shows reactivity with Chemical samples. The MA5-14725 immunogen is caffeine-3-KLH. Product MA514725 is a smaller package size of MIC0401 (formerly sold as a Seradyn product).

Caffeine is a methylxanthine alkaloid found in the seeds, nuts, or leaves of a number of plants native to South America and East Asia that is structurally related to adenosine and acts primarily as an adenosine receptor antagonist with psychotropic and anti-inflammatory activities. Upon ingestion, caffeine binds to adenosine receptors in the central nervous system (CNS), which inhibits adenosine binding. This inhibits the adenosine-mediated downregulation of CNS activity; thus, stimulating the activity of the medullary, vagal, vasomotor, and respiratory centers in the brain. This agent also promotes neurotransmitter release that further stimulates the CNS. The anti-inflammatory effects of caffeine are due the nonselective competitive inhibition of phosphodiesterases (PDEs). Inhibition of PDEs raises the intracellular concentration of cyclic AMP (cAMP), activates protein kinase A, and inhibits leukotriene synthesis, which leads to reduced inflammation and innate immunity. [National Center for Biotechnology Information. PubChem Compound Database; CID=2519].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caffeine
Applications ELISA, Immunoprecipitation, Radioimmune Assays (RIA)
Classification Monoclonal
Clone F1-P2B1G1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.4
Gene Alias 7-Trimethylxanthine; C8H10N4O2; Guaranine; Methyltheobromine
Host Species Mouse
Immunogen Caffeine-3-KLH.
Purification Method Ion-exchange chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2b
Target Molecule Chemical
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Safety and Handling

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