CAL Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No.	Quantity
50-156-3099	100 μL

Catalog No. 50-156-3099 Supplier Bethyl Laboratories, Inc Supplier No. A302641A

Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan

Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.

Specifications

• Antigen: CAL
• Applications: Immunoprecipitation
• Classification: Polyclonal
• Concentration: 1 mg/ml
• Conjugate: Unconjugated
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene: GOPC
• Gene Accession No.: Q9HD26
• Gene Alias: PDZ protein interacting specifically with TC10; CFTR-associated ligand; Fused in glioblastoma
• Gene Symbols: GOPC
• Host Species: Rabbit
• Immunogen: Between 275 and 325
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 57120
• Target Species: Human
• Content And Storage: 4° C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG