Invitrogen™ Calbindin D28K Monoclonal Antibody (CB-955)

Catalog No.	Quantity
PIMA532993	100 μg

Catalog No. PIMA532993 Supplier Invitrogen™ Supplier No. MA532993

Description

Mouse Monoclonal Antibody

Reconstitute with 1 mL of PBS buffer to yield a concentration of 100 μg/mL. Positive Control - WB: Rat Brain Tissue, Rat Brain Tissue, Rat Kidney Tissue, Rat Lung Tissue, rat brain tissue, rat kidney tissue, mouse brain tissue. IHC: Mouse Kidney Tissue, Human Intestinal Cancer Tissue, Rat Kidney Tissue, Human Mammary Cancer Tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calbindin-D-28K (also termed vitamin D-dependent calcium-binding protein, or cholecalcin), is a highly conserved 28kDa calcium binding protein, with broad tissue distribution. It belongs, together with calmodulin, S-100, parvalbumin, troponin C and other proteins, to a family of low molecular weight calcium-binding proteins (CaBPs). These CaBPs have homologous primary structures, which contain conserved polypeptide folds of the EF-hand type for Ca2+ binding. Calbindin-D-28K is found predominantly in subpopulations of central and peripheral nervous system neurons, and in certain epithelial nervous system neurons, and in certain epithelial cells involved in Ca2+ transport such as distal tubular cells and cortical collecting tubules of the kidney, and in enteric neuroendocrine cells.

Specifications

• Antigen: Calbindin D28K
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: CB-955
• Concentration: 100 μg/mL
• Conjugate: Unconjugated
• Formulation: Ascites, 1.2% sodium acetate with 2mg BSA and 0.01mg sodium azide
• Gene: CALB1
• Gene Accession No.: P04467, P05937, P07171, P12658
• Gene Alias: Brain-2; CAB27; CaBP28K; Calb; CALB1; Calb-1; Calbindin; calbindin 1; calbindin 1, (28kD); calbindin 1, 28 kD; calbindin 1, 28kDa; calbindin D28; calbindin-28K; calbindin-D (28k); CalbindinD28K; CB; cerebellar Ca-binding protein spot 35 protein; cerebellar Ca-binding protein, spot 35 protein; D-28K; PCD-29; RTVL-H protein; spot 35 protein; Vitamin D-dependent calcium-binding protein, avian-type
• Gene Symbols: CALB1
• Host Species: Mouse
• Immunogen: Bovine kidney calbindin-D.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 12307, 539930, 793, 83839
• Target Species: Human, Mouse, Rat, Bovine
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1