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MilliporeSigma™ Calbiochem™ Ru360

Catalog No. 5574401SET Shop All MilliporeSigma Products
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500 μg
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55-744-01SET 1 Set
55-744-0500UG 500 μg
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Description

A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).

A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min). Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.
TRUSTED_SUSTAINABILITY

Specifications

Color Reddish Brown
Target Proteins Ca2+ uptake into mitochondria in vitro
Molecular Formula C2H26Cl3N8O5Ru2
Formula Weight 550.8g/mol
Solubility deoxygenated H2O
Content And Storage Hygroscopic, Protect from light
Form Solid
Quantity 1 Set
Purity 97% by capillary electrophoresis
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