Invitrogen™ Calcitonin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA137211

Catalog No. 01-673-145

Description

This antibody is predicted to react with mouse and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is thyroid or medullary carcinoma.

Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Specifications

• Antigen: Calcitonin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALCA
• Gene Alias: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; CA; Cal1; CAL6; CALC; CALC1; Calca; Calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin gene related peptide I precursor; Calcitonin gene-related peptide; calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin precursor; calcitonin related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; calcitonin; calcitonin gene-related peptide 1; calcitonin-like; calcitonin-related polypeptide alpha; CCALCI; CCP; Cgrp; CGRP1; CGRP-1; CGRPI; CGRP-I; CT; Ctn; katacalcin; katacalcin (KC); KC; PCT; PDN-21; prepro-alpha-calcitonin gene-related peptide; procalcitonin; RATCAL6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 796
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.027 mg/mL
• Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.6
• Gene Accession No.: P01258, P06881
• Gene Symbols: CALCA
• Immunogen: Synthetic human calcitonin 1-32 amino acid peptide.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG