Invitrogen™ Calcitonin Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 720296

Catalog No. 72-029-6

Description

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature. This antibody is predicted to react with Monkey, Pig, Cat and Rat.

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.

Specifications

• Antigen: Calcitonin Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALCR
• Gene Alias: C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116506, 12311, 799
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
• Gene Accession No.: P30988, P32214, Q60755
• Gene Symbols: CALCR
• Immunogen: Peptide corresponding to Human CALCR (aa 490-508).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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