Invitrogen™ Calcitonin Receptor Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA533379

Catalog No. PIPA533379

Description

Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Marmoset (95%) Gibbon, Monkey (90%) Rabbit (85%) Panda, Dog, Horse (80%).

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.

Specifications

• Antigen: Calcitonin Receptor
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CALCR
• Gene Alias: C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 799
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P30988
• Gene Symbols: CALCR
• Immunogen: Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Calcitonin Receptor.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG