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Invitrogen™ Calcitonin Receptor Polyclonal Antibody
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50 μg
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PIPA533379 50 μg
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Catalog No. PIPA533379 Supplier Invitrogen™ Supplier No. PA533379
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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Marmoset (95%) Gibbon, Monkey (90%) Rabbit (85%) Panda, Dog, Horse (80%).

The Calcitonin Receptor inhibits bone resorption. This receptor is expressed during development and is involved in morphogenesis. Three alternatively spliced Calcitonin Receptor isoforms have been identified. In addition to binding calcitonin, the Calcitonin Receptor can complex with RAMP3 (receptor activity modifying protein) to bind amylin, which regulates pancreatic islet function and is involved in Type II diabetes. The Calcitonin Receptor has been reported in artery, blood, bone, brain, kidney, lung, placenta, prostate, skeletal muscle, and thyroid. ESTs have been isolated from bone, embryo, kidney, and melanocyte/uterus/fetal heart libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calcitonin Receptor
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene CALCR
Gene Accession No. P30988
Gene Alias C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
Gene Symbols CALCR
Host Species Rabbit
Immunogen Synthetic 20 amino acid peptide from N-terminal extracellular domain of human Calcitonin Receptor.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 799
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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