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Invitrogen™ Calcium Channel beta-4 Polyclonal Antibody
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Catalog No. 01674825
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100 μg
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Catalog No. Quantity
01-674-825 100 μg
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Catalog No. 01-674-825 Supplier Invitrogen™ Supplier No. PA112671
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Description

Rabbit Polyclonal Antibody

A suggested positive control for this product is rat brain lysate.

This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy and juvenile myoclonic epilepsy. Multiple transcript variants encoding different isoforms have been found for this gene.
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Specifications

Antigen Calcium Channel beta-4
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.08% sodium azide
Gene Cacnb4
Gene Accession No. O00305
Gene Alias 3110038O15Rik; CAB4; Cacnb4; CACNLB4; calcium channel beta 4 subunit; calcium channel voltage-dependent subunit beta 4; calcium channel, voltage-dependent, beta 4 subunit; calcium voltage-gated channel auxiliary subunit beta 4; Cchb4; dihydropyridine-sensitive L-type, calcium channel beta-4 subunit; EA5; EIG9; EJM; EJM4; EJM6; lh; OTTHUMP00000207247; OTTHUMP00000207249; Voltage-dependent L-type calcium channel subunit beta-4
Gene Symbols Cacnb4
Host Species Rabbit
Immunogen Synthetic peptide, conjugated to KLH, corresponding to the rat calcium channel beta4 subunit.
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 785
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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