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Invitrogen™ Calpain 11 Polyclonal Antibody
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Catalog No. PIPA5101478
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PIPA5101478 100 μL
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Catalog No. PIPA5101478 Supplier Invitrogen™ Supplier No. PA5101478
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CAPN11.

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain 11
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CAPN11
Gene Accession No. Q9UMQ6
Gene Alias calcium-activated neutral proteinase 11; calcium-activated neutral proteinase 11 {ECO:0000250; calcium-dependent thiol protease; calpain 11; calpain 11 {ECO:0000312; calpain11; Calpain-11; calpain-11; LOW QUALITY PROTEIN: calpain-11; CANP 11; CANP 11 {ECO:0000250; Capn11; capn11 {ECO:0000312; EMBL:AAH97256.1}; HIP2; LIG; RGD:1302946}; UniProtKB:Q9UMQ6}
Gene Symbols CAPN11
Host Species Rabbit
Immunogen A synthesized peptide derived from human CAPN11(Accession Q9UMQ6), corresponding to amino acid residues A405-H455.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11131
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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