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Calpain S1 Monoclonal Antibody (156), Invitrogen™

Catalog No. MA3943
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100 μL
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Catalog No. Quantity
MA3943 100 μL
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Catalog No. MA3943 Supplier Thermo Scientific Supplier No. MA3943

Description

Mouse Monoclonal Antibody

MA3-943 detects calpain-28 kDa subunit from bovine platelet, skeletal and heart muscle and human tissues. This antibody does not cross-react with the human 80 kDa m-calpain subunit. MA3-943 has been successfully used in Western blot and immunofluorescence procedures. By Western blot, this antibody detects a 28 kDa protein representing the 28 kDa subunit of calpain from bovine heart extract. The MA3-943 antigen is purified bovine skeletal muscle 28 kDa calpain subunit.

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain S1
Applications Immunocytochemistry, Western Blot
Classification Monoclonal
Clone 156
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites diluted in PBS with 0.05% sodium azide
Gene CAPNS1
Gene Accession No. P04632, P13135
Gene Alias 30K; Calcium-activated neutral proteinase small subunit; calcium-dependent protease; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CALPAIN4; CANP; CANP small subunit; CANPS; Capa4; Capa-4; Capn4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e; small pol; unknown protein
Gene Symbols CAPNS1
Host Species Mouse
Immunogen Purified bovine skeletal muscle 28 kDa calpain subunit.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 281664, 826
Target Species Bovine, Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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