Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 01674303

Invitrogen™ Calpain S1/S2 Monoclonal Antibody (28F3)
GREENER_CHOICE

Catalog No. 01674303
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
01-674-303 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 01-674-303 Supplier Invitrogen™ Supplier No. MA112433
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

This antibody specifically recognizes the 28 to 30 kD small subunit of Calpain 1 and Calpain 2 (mu calpain and m calpain). It recognizes both native and denatured protein in ELISA, Western Blot and Immunoprecipitation.

The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and m-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. Whereas m-calpain requires millimolar (mM) levels of calcium, m-calpain is active at micromolar (mM) concentrations of Ca++. In addition to the ubiquitously expressed m- and m- calpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calpain S1/S2
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 28F3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 3mM sodium azide; pH 7.5
Gene CAPNS1
Gene Accession No. P04632, P13135, Q96L46
Gene Alias 2310005G05Rik; 30K-2; calcium-activated neutral proteinase 2; Calcium-activated neutral proteinase small subunit; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease small subunit 2; calcium-dependent protease, small subunit; calpain 2; calpain 2, (m/II) large subunit; calpain 2, large [catalytic] subunit; calpain 2, large subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain large polypeptide L2; Calpain M-type; calpain regulatory subunit; Calpain small subunit 1; calpain small subunit 2; calpain, large polypeptide L2; calpain, small polypeptide; calpain, small subunit 1; calpain, small subunit 2; calpain-2 catalytic subunit; Calpain-2 large subunit; CALPAIN4; CANP; CANP 2; CANP small subunit; CANP2; CANPL2; CANPml; CANPS; Capa4; Capa-4; CAPN2; Capn4; CAPNS; CAPNS1; Capns2; CDPS; CSS1; CSS2; D7Ertd146e; M-calpain; mCANP; Millimolar-calpain
Gene Symbols CAPNS1, CAPNS2
Host Species Mouse
Immunogen Human Calpain protein purified from placenta.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100300424, 281664, 826, 84290
Target Species Human, Bovine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.