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Invitrogen™ Calreticulin Monoclonal Antibody (1G6A7)
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Catalog No. FEMA515382
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100 μg
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Catalog No. Quantity
FEMA515382 100 μg
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Catalog No. FEMA515382 Supplier Invitrogen™ Supplier No. MA515382
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Description

Mouse Monoclonal Antibody

MA5-15382 targets Calreticulin in IF, IHC, Flow and WB applications and shows reactivity with Human, non-Human primate, and mouse samples. The MA5-15382 immunogen is synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH. MA5-15382 detects Calreticulin which has a predicted molecular weight of approximately 48kDa.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calreticulin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 1G6A7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene CALR
Gene Accession No. P14211, P27797
Gene Alias Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Gene Symbols CALR
Host Species Mouse
Immunogen Synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12317, 811
Target Species Human, Mouse, Monkey
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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