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Invitrogen™ Calreticulin Monoclonal Antibody (7B1)
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Catalog No. PIMA545067
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100 μL
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PIMA545067 100 μL
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Catalog No. PIMA545067 Supplier Invitrogen™ Supplier No. MA545067
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Description

Mouse Monoclonal Antibody

Calreticulin Monoclonal Antibody for Flow, ICC/IF, IHC (P), Western Blot

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Calreticulin
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7B1
Concentration 2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide, pH 7.4
Gene CALR
Gene Accession No. P27797
Gene Alias Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Gene Symbols CALR
Host Species Mouse
Immunogen Recombinant full length protein corresponding to Human Calretinin aa 1 to the C-terminus.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 811
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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