Invitrogen™ Calreticulin Recombinant Mouse Monoclonal Antibody (2E2)

Mouse Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550256

Catalog No. FEMA550256

Description

Calreticulin Recombinant Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), Flow, ELISA

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.

Specifications

• Antigen: Calreticulin
• Classification: Recombinant Monoclonal
• Concentration: 0.833 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene Accession No.: P14211, P27797
• Gene Symbols: CALR
• Immunogen: Recombinant Human CALR protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 2E2
• Conjugate: Unconjugated
• Gene: CALR
• Gene Alias: Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12317, 811
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid