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Calsequestrin Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735418 Shop All Proteintech Group Inc Products
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50-173-5418 150 μL
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Catalog No. 50-173-5418 Supplier Proteintech Group Inc Supplier No. 266651AP150UL
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Description

Rabbit Polyclonal Antibody

The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

Specifications

Antigen Calsequestrin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CASQ1
Gene Accession No. O09165, P31415
Gene Alias Calmitin, Calsequestrin 1, CASQ, CASQ1, PDIB1
Gene Symbols Casq1
Host Species Rabbit
Immunogen Calsequestrin Fusion Protein Ag24684
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12372, 844
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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