Invitrogen™ Human CAMK2B (CaMKII Beta), His Tag Recombinant Protein

Catalog No.	Quantity
PR7771A	100 μg
PV4205	10 μg

Catalog No. PR7771A Supplier Invitrogen™ Supplier No. PR7771A

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Specifications

• Accession Number: Q13554
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50mM tris with 2mM DTT, 50% glycerol, 0.02% Triton X-100, 150mM NaCl, 0.5mM EDTA and no preservative; pH 7.5
• Gene ID (Entrez): 816
• Molecular Weight (g/mol): 60.5 kDa
• Name: Human CAMK2B (CaMKII Beta), His Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: Ca++/calmodulin-dependent protein kinase II beta subunit; calcium/calmodulin dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase II, beta; calcium/calmodulin-dependent protein kinase type II beta chain; calcium/calmodulin-dependent protein kinase type II subunit beta; CaM kinase II beta subunit; caM kinase II subunit beta; CAM2; CaMK II; CAMK2; CAMK2B; Camk2d; CAMKB; caMK-II subunit beta; caM-kinase II beta chain; Ck2b; hypothetical protein LOC525416; MGC29528; proline rich calmodulin-dependent protein kinase; β CaMKII; βCaMKII
• Common Name: CaMKII beta
• Gene Symbol: CAMK2B
• Kinase Family: CAMK2 Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Kinase Group: Ser⁄Thr Kinases: CAMK Group
• Shipping Condition: Dry Ice
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Signal Transduction

Safety and Handling

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