CAMK2B Monoclonal Antibody (OTI8D9), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-2070	100 μL

Catalog No. 50-168-2070 Supplier OriGene Supplier No. TA808345

Description

Mouse Monoclonal Antibody

The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+ and calmodulin (CaM) and has been implicated in regulation of the cell cycle and transcription. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

Specifications

• Antigen: CAMK2B
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI8D9
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: CAMK2B
• Gene Accession No.: Q13554
• Gene Alias: CAM2, CAMK2, CAMKB, MRD54
• Gene Symbols: CAMK2B
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 311-385 of human CAMK2B produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 816
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1