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Invitrogen™ CAMSAP1 Polyclonal Antibody
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Catalog No. PIPA554999
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PIPA554999 100 μL
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Catalog No. PIPA554999 Supplier Invitrogen™ Supplier No. PA554999
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPTDPGLDSA LEPSGDPHGK CLFDSYRLHD ESNQRTLTLS SSKDANILSE QMSLKEVLDA SVKEVGSSSS DVSGKESVPV EEPLRSRASL IEVDLSDLK Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 65%.

Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:19508979, PubMed:21834987, PubMed:24486153, PubMed:24706919, PubMed:24117850). Specifically recognizes growing microtubule minus-ends and stabilizes microtubules (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation (PubMed:24486153, PubMed:24706919). Through interaction with spectrin may regulate neurite outgrowth (PubMed:24117850). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAMSAP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CAMSAP1
Gene Accession No. Q5T5Y3
Gene Alias 9530003A05Rik; C77823; calmodulin regulated spectrin associated protein 1; calmodulin regulated spectrin-associated protein 1; calmodulin-regulated spectrin-associated protein 1; Camsap1; DKFZp434F195; FLJ31228; PRO2405; RGD1565022
Gene Symbols CAMSAP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CAMSAP1. Recombinant protein control fragment (Product #RP-92950).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 157922
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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