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Invitrogen™ Cannabinoid Receptor 1 Polyclonal Antibody
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Catalog No. PA1743
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100 μL
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PA1743 100 μL
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Catalog No. PA1743 Supplier Invitrogen™ Supplier No. PA1743
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Description

Rabbit Polyclonal Antibody

PA1-743 detects cannabinoid receptor 1 (CB1) from human and rat tissues as well as transfected rat CB1. PA1-743 has been successfully used in Western blot and immunocytochemistry procedures. By Western blot, this antibody detects an ~52 kDa protein representing CB1 from rat brain homogenate. Immunocytochemical staining of CB1 in AtT20 cells transfected with the rat CB1 gene with PA1-743 yields a pattern consistent with plasma membrane staining. PA1-743 antigen is a fusion protein containing the first 99 amino acid residues of human CB1.

This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cannabinoid Receptor 1
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene CNR1
Gene Accession No. P20272, P21554
Gene Alias brain-type cannabinoid receptor; CANN6; Cannabinoid receptor 1; cannabinoid receptor 1 (brain); CB1; CB1 cannabinoid receptor; CB1 receptor; CB1A; CB1K5; CB1R; CB-R; central cannabinoid receptor; CNR; Cnr1; HGNC:2159; OTTHUMP00000016839; RP1-23D17.1; seven transmembrane domains; G-protein-coupled receptor; Skr6; SKR6R; striatal cannabinoid receptor type 1 protein
Gene Symbols CNR1
Host Species Rabbit
Immunogen A fusion protein containing the first 99 amino acid residues from human CB1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1268, 25248
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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