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Invitrogen™ Carboxypeptidase B2 Monoclonal Antibody (5024)
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Catalog No. PIMA143023
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100 μg
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Catalog No. Quantity
PIMA143023 100 μg
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Catalog No. PIMA143023 Supplier Invitrogen™ Supplier No. MA143023
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Description

Mouse Monoclonal Antibody

MA1-43023 detects TAFI in human samples. MA1-43023 has successfully been used in Western Blot, ELISA, and Inhibition Assay applications. MA1-43023 was derived from human TAFI and activated TAFI.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Carboxypeptidase B2
Applications ELISA, Inhibition Assays, Western Blot
Classification Monoclonal
Clone 5024
Concentration 10 mg/mL
Conjugate Unconjugated
Formulation 50% water with 50% glycerol and no preservative
Gene CPB2
Gene Accession No. Q96IY4
Gene Alias 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
Gene Symbols CPB2
Host Species Mouse
Immunogen Human TAFI.
Purification Method SDS-PAGE
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1361
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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