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Invitrogen™ Cardiac Troponin C Polyclonal Antibody
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Catalog No. PIPA583741
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100 μL
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PIPA583741 100 μL
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Catalog No. PIPA583741 Supplier Invitrogen™ Supplier No. PA583741
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MDDIYKAAVE QLTEEQKNEF KAAFDIFVLG AEDGCISTKE LGKVM Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 100%.

Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cardiac Troponin C
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.30 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Tnnc1
Gene Accession No. P63316
Gene Alias AI874626; cardiac 3; cardiac troponin C; Cardiac troponin I; CMD1FF; CMD1Z; CMD2A; CMH13; CMH7; cTnC; cTnI; MGC116817; RCM1; slow twitch skeletal/cardiac muscle troponin C; Tn1; TnC; TN-C; Tncc; Tni; TNN I3; TNNC; TNNC 1; Tnnc1; TNNI3; troponin C type 1 (slow); troponin C, cardiac/slow skeletal; troponin C, slow skeletal and cardiac muscles; troponin C1, slow; troponin C1, slow skeletal and cardiac type; Troponin I; Troponin I cardiac; TroponinI
Gene Symbols Tnnc1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TNNC1. Recombinant protein control fragment (Product #RP-106074).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7134
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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