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Invitrogen™ CARKL Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA549892
Description
The antibody detects endogenous levels of total CARKL protein.
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
Specifications
CARKL | |
Polyclonal | |
Unconjugated | |
SHPK | |
4930431K22Rik; AI194947; AW260459; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
23729, 287479, 74637 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q9D5J6, Q9UHJ6 | |
SHPK | |
Synthesized peptide derived from N-terminal of human CARKL. | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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