Invitrogen™ CARKL Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA549892

Catalog No. PA549892

Description

The antibody detects endogenous levels of total CARKL protein.

The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.

Specifications

• Antigen: CARKL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SHPK
• Gene Alias: 4930431K22Rik; AI194947; AW260459; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23729, 287479, 74637
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9D5J6, Q9UHJ6
• Gene Symbols: SHPK
• Immunogen: Synthesized peptide derived from N-terminal of human CARKL.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG