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Invitrogen™ CAS Polyclonal Antibody
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Catalog No. PIPA583402
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100 μL
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PIPA583402 100 μL
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Catalog No. PIPA583402 Supplier Invitrogen™ Supplier No. PA583402
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HGITQANELV NLTEFFVNHI LPDLKSANVN EFPVLKADGI KYIMIFRNQV PKEHLLVSIP LLINHLQAES IVVHTYAAHA LERLFTMRGP NNATLF Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 97%.

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CAS
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CSE1L
Gene Accession No. P55060
Gene Alias 2610100P18Rik; AA407533; Capts; CAS; Cellular apoptosis susceptibility protein; chromosome segregation 1 like; chromosome segregation 1-like (S. cerevisiae); chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; CSE1 chromosome segregation 1-like (yeast); CSE1L; Exp2; exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO2
Gene Symbols CSE1L
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CSE1L. Recombinant protein control fragment (Product #RP-102804).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1434
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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