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Invitrogen™ Cas12j Monoclonal Antibody (5F95)

Catalog No. PIMA547349
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500 μL
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PIMA547349 500 μL
PIMA547448 100 μL
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Catalog No. PIMA547349 Supplier Invitrogen™ Supplier No. MA547349
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Description

Mouse Monoclonal Antibody

Cas12j Monoclonal Antibody for Western Blot, ICC/IF

There has been much recent interest in gene editing and other genetic manipulations by CRISPR-Cas family enzymes. The lab of Nobel prize winner Jennifer Doudna characterized these Cas enzymes and showed that they could be used to perform CRISPR, but had the significant advantage that they were much smaller in molecular size than other Cas family enzymes such as the widely used Cas9 enzymes from S. pyogenes and S. aureus. One of these enzymes is referred to as Cas theta and also known as Cas-12j. The use of such smaller Cas family enzymes leaves more room for other nucleic acid sequences in AAV and other viral vectors which typically have a limited DNA capacity, thus allowing more versatility for new CRISPR based manipulations.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cas12j
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5F95
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene Alias Cas theta
Host Species Mouse
Immunogen Recombinant Cas theta/Cas-12j expressed in and purified from E. coli.
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
Target Molecule Chemical
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