Invitrogen™ Cas12j Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5143500	Invitrogen™ PA5143500	500 μL
PIPA5143597	Invitrogen™ PA5143597	100 μL

Description

Cas12j Polyclonal Antibody for Western Blot, ICC/IF

There has been much recent interest in gene editing and other genetic manipulations by CRISPR-Cas family enzymes. The lab of Nobel prize winner Jennifer Doudna characterized these Cas enzymes and showed that they could be used to perform CRISPR, but had the significant advantage that they were much smaller in molecular size than other Cas family enzymes such as the widely used Cas9 enzymes from S. pyogenes and S. aureus. One of these enzymes is referred to as Cas theta and also known as Cas-12j. The use of such smaller Cas family enzymes leaves more room for other nucleic acid sequences in AAV and other viral vectors which typically have a limited DNA capacity, thus allowing more versatility for new CRISPR based manipulations.

Specifications

• Antigen: Cas12j
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Chemical
• Gene Alias: Cas theta
• Primary or Secondary: Primary
• Purification Method: Affinity chromatography

• Concentration: 1 mg/mL
• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 5 mM sodium azide
• Immunogen: Full length Cas12j expressed in and purified from E. coli.
• Product Type: Antibody