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CASC5 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Description
The recommended shelf life for this product is 1 year from date of receipt.
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
Specifications
Specifications
| Antigen | CASC5 |
| Applications | Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 1 mg/ml |
| Conjugate | Unconjugated |
| Formulation | phosphate, tris citrate with 0.09% sodium azide; pH 7-8 |
| Gene | KNL1 |
| Gene Accession No. | Q8NG31 |
| Gene Alias | Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1 |
| Gene Symbols | KNL1 |
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