Caspase 2 Mouse anti-Human, Clone: 2G4C2, Proteintech

Catalog No.	Quantity
50-173-6938	150 μL

Catalog No. 50-173-6938 Supplier Proteintech Group Inc Supplier No. 665171IG150UL

Description

Mouse Monoclonal Antibody

This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.

Caspase 2 gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: Caspase 2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: 2G4C2
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: CASP2
• Gene Accession No.: P42575
• Gene Alias: CASP 2, CASP2, Caspase 2, Caspase2, ICH 1L, ICH 1L/1S, ICH1, NEDD 2, NEDD2, Protease ICH 1
• Gene Symbols: CASP2
• Host Species: Mouse
• Immunogen: Caspase 2 Fusion Protein Ag20141
• Purification Method: Protein A
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 835
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1