Thermo Scientific™ Lab Vision™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures.

Catalog Number	Mfr. No.	Formulation	Quantity
RB1197B	Thermo Scientific™ RB1197B	Biotinylated Ab with BSA and Azide	1mL
RB1197R1	Thermo Scientific™ RB1197R1	Ready-to-use for IHC (UVLP)	1mL
RB1197B0	Thermo Scientific™ RB1197B0	Biotinylated Ab with BSA and Azide	100μL
RB1197B1	Thermo Scientific™ RB1197B1	Biotinylated Ab with BSA and Azide	500μL
RB1197P	Thermo Scientific™ RB1197P	Purified Ab with BSA and Azide	1mL
RB1197P0	Thermo Scientific™ RB1197P0	Purified Ab with BSA and Azide	100μL
RB1197P1	Thermo Scientific™ RB1197P1	Purified Ab with BSA and Azide	500μL
RB1197P1ABX	Thermo Scientific™ RB1197P1ABX	Ab without BSA/Azide (Frozen)	500μL
RB1197PABX	Thermo Scientific™ RB1197PABX	Ab without BSA/Azide (Frozen)	1mL
RB1197R7	Thermo Scientific™ RB1197R7	Ready-to-use for IHC (UVLP)	7mL

Description

Ensure accurate, reproducible results in immunohistochemistry, western blotting and immunoprecipitation procedures with Thermo Scientific™ Caspase 3 (CPP32) Ab-4, Rabbit Polyclonal Antibody.

Caspase 3 is ubiquitously expressed and like other caspases is synthesized as an inactive (32 kDa) proenzyme. Upon activation, Caspase 3 is cleaved at Asp28-Ser29 and Asp175-Ser176 thereby generating two subunits of 17 kDa and 12 kDa, respectively. Recent studies have implicated that Caspase 3 is associated with the induction of apoptosis. Activation of Caspase 3 occurs in response to a variety of apoptotic inducers including Fas-mediated apoptosis.

Host Species: Rabbit

Isotype: IgG

Species Reactivity: Human, Mouse, Rat, Monkey, Rabbit, Hamster, Cow, Sheep, Pig and Dog. Others not tested.

Epitope: Not determined

Immunogen: Recombinant full-length human caspase 3 protein

Molecular Weight: 32 kDa

Positive Control: Jurkat cells, Tonsil

Cellular Localization: Predominantly cytoplasmic with some nuclear staining

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting
• Immunoprecipitation (Denatured verified)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: Caspase 3 (CPP32) Ab-4
• Classification: Polyclonal
• Regulatory Status: RUO
• Type: Primary
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Host Species: Rabbit
• Research Discipline: Apoptosis
• Immunogen: Recombinant full length human caspase 3 protein