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Invitrogen™ Caspase 3 Monoclonal Antibody (74T2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 437800

Encompass_Preferred

Catalog No. 43-780-0


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Description

Description

Caspase 3 Monoclonal Antibody for Western Blot, ICC/IF, IHC (P), IP

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Caspase 3
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide; pH 7.4
P42574, P55213, P70677
CASP3
Recombinant protein derived from the N-terminus of human Caspase 3 protein.
100 μg
Primary
Human, Mouse, Rat, Monkey, Horse
Antibody
IgG1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
74T2
Unconjugated
CASP3
A830040C14Rik; AC-3; Apopain; Apopain precursor; Casp3; CASP-3; caspase 3; Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis related cysteine protease; Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease); caspase 3, apoptosis-related cysteine peptidase; caspase 3, apoptosis-related cysteine protease; Caspase3; caspase-3; Caspase-3 subunit p12; Caspase-3 subunit p17; Caspase-3-like protein; CC3; Cpp32; CPP-32; CPP32B; CPP32beta; cysteine protease CPP32; cysteine protease; CPP32; apopain; ICE3; IRP; LICE; mldy; PARP cleavage protease; procaspase3; protein Yama; SCA-1; SREBP cleavage activity 1; Yama; yama protein
Mouse
Protein A
RUO
100034083, 12367, 25402, 836
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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