Invitrogen™ Caspase 6 Monoclonal Antibody (C1)

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA541562	Invitrogen™ MA541562	200 μL
PIMA543919	Invitrogen™ MA543919	20 μL

Description

Caspase 6 Monoclonal Antibody for Western Blot, IHC (P)

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

• Antigen: Caspase 6
• Concentration: 1 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: Q3T0P5
• Gene ID (Entrez): 538409
• Immunogen: Recombinant protein Caspase 6.
• Product Type: Antibody

• Clone: C1
• Content And Storage: -20°C
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1 κ
• Target Species: Bovine
• Gene: Casp6
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
• Gene Symbols: Casp6
• Primary or Secondary: Primary
• Purification Method: Protein A/G