Invitrogen™ Caspase 6 Monoclonal Antibody (D4)

Catalog No.	Quantity
MA566118	200 μL

Catalog No. MA566118 Supplier Invitrogen™ Supplier No. MA566118

Description

Mouse Monoclonal Antibody

Caspase 6 Monoclonal Antibody for Western Blot, ICC/IF, IHC

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

Specifications

• Antigen: Caspase 6
• Applications: Immunohistochemistry, Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: D4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene: Casp6
• Gene Accession No.: O35397, P55212
• Gene Alias: apoptotic protease MCH-2; CASP6; CASP-6; caspase 6; caspase 6, apoptosis-related cysteine peptidase; caspase 6, apoptosis-related cysteine protease; caspase-6; Caspase-6 subunit p11; Caspase-6 subunit p18; mCASP-6; MCH2
• Gene Symbols: Casp6
• Host Species: Mouse
• Immunogen: Recombinant Caspase 6 (CASP6) (Ala194-Asn293).
• Purification Method: Protein A/G
• Quantity: 200 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 83584, 839
• Target Species: Human, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid